The objective of this roadmap is to ensure that an Independent Panel for Evidence for Action against Antimicrobial Resistance (IPEA) is established and commences its work as soon as practicable in 2025. The roadmap outlines the steps necessary for establishing the panel, facilitated by the Quadripartite organizations, in response to the 79^th United Nations General Assembly (UNGA) Political Declaration on antimicrobial resistance (AMR). This document details an open and transparent process following the key principle of “form follows function” and drawing on past discussions and lessons from other science-policy interfaces such as “Strengthening the Science-Policy Interface: A gap analysis” (2017);  “Assessment of options for strengthening the science-policy interface at the international level for the sound management of chemicals and waste” (2020) and “Reflecting on the Past and Imagining the Future: A contribution to the dialogue on the Science-Policy Interface”( 2022). 

AMR is a global, multifaceted threat that undermines the effectiveness of modern medicine, prolongs illness, reduces agricultural productivity, and disrupts economies. It is also linked to pollution and the environment, and hampers progress towards attainment of the Sustainable Development Goals. As a cross-sectoral challenge affecting human health, animal health, agrifood systems, and the environment, AMR requires a coordinated, science-driven and global response.

In 2019, the Inter-Agency Coordination Group on AMR (IACG) recommended establishing an IPEA as part of AMR global governance structures alongside the Global Leaders Group (GLG) on AMR and the AMR Multistakeholder Partnership Platform (MSPP). While these two structures are already operational, IPEA remains to be established. The 79th UNGA Political Declaration called on the Quadripartite organizations to establish IPEA by 2025, ensuring an inclusive and transparent consultative process with all Member States on its composition, mandate, scope and deliverables, and serves as the guide for this roadmap.